Looking at the digital version of the UK edition, the main issue is 112 pages, and comes with the 96 page On Time watch supplement, which is fronted by Alicia Vikander.
The Vanities person is Ewan McGregor's daughter, Esther. Someone from Blink-182 talks about having cancer, the VF royal correspondent talks about having cancer.
In addition to the cover story, there appears to be the usual fold-out section with backstage photos from the Vanity Fair Oscars Party as part of a Chanel ad, plus the mystery of Barron Trump, a profile of Democrat Elissa Slotkin, an article on aviation sabotage, and a feature with WWE wrestler Roman Reigns / Joe Anoa'i.
Ruven Afanador photographs some alumni of Juillard, and the F1 Academy is about women drivers. The back page Proust Questionnaire is Bernadette Peters.
This issue feels like a hybrid version of Vanity Fair and GQ, which I don't mind, because I don't read men's magazines, so that type of content represents something different for me. Your mileage may vary.