For anyone considering taking accutane, heres my two cents...
I've just stopped taking my accutane medication and my skin is pretty much perfect now (aside from the scarring). I haven't got a pimple in months now, and i've become one of those girls who sighs at the tiniest pimple now, before that used to be an everyday thing.
I didn't actually notice much of the side effects that have been mentioned, just dry lips and a little bit of lethargy at times (however, that might not be the medication and just my lifestyle/eating habits in general). I think I had more negative feelings when I had terrible skin then when I was on the medication and my skin finally started clearing up.
If you have terrible skin like I had, I definetly recommend trying it. Since i've been on the medication i've had so many compliments on my skin about how it's just cleared up completely, and I don't regret taking it one bit! A lot of people were warning me about the medication beforehand and how I should be taking 'natural' remedies, but seriously.. when your skin is THAT bad you really need to go on this stuff. The 'natural' remedies, I find, is more for the occasional, everyday acne.
That being said, the medication should only be tried if your skin is terrible and persistant after other things haven't worked. Definitly exhaust all other options before going on the medication!